Ubiquinol's impact on blood clottingUbiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial.
Directly addresses inflammatory markers.
With a focus on antiphospholipid syndrome (APS), we set out to understand how ubiquinol, a reduced form of coenzyme Q10, influences markers related to blood clotting and inflammation. Our study was a well-structured, randomized, placebo-controlled trial involving 36 patients with APS, where we administered 200 mg of ubiquinol daily for one month.
We found that supplementation with ubiquinol notably improved the function of blood vessels and reduced the expression of prothrombotic and inflammatory markers present in monocytes. This suggests that ubiquinol plays a role in reducing the risk of blood clots by enhancing endothelial function and dampening inflammatory responses.
Moreover, our results revealed a significant decrease in harmful molecules and a shift in mitochondrial dynamics, which could further support cardiovascular health. Notably, we also observed positive changes in specific microRNAs and gene expressions linked to atherosclerosis, reinforcing the multifaceted benefits of this treatment.
In summary, ubiquinol has the potential to serve as a beneficial adjunct therapy for managing the thrombotic risks associated with APS, especially given its lack of significant side effects. Our findings indicate that ubiquinol could be a promising option for patients seeking to improve their overall condition related to blood clotting.
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